Infectious Pancreatic Necrosis (IPN)
Infectious Pancreatic Necrosis Virus (IPNV)
Animal model: Atlantic salmon
Source of CAT isolates:
Applications: Vaccine development, functional nutrition....
Type of model: Cohabitation
Clinical Signs of Disease in our Model: Haemorrhaging of viscera, darkening of skin
Challenge conditions: 10-15C; 25-35ppt
Other end points: Periodic sampling for histopathology, seronversion assays, and gene response
Starting Fish Size: 40-150 grams
Atlantic Salmon
Summary:
Representative survival curve of cohab fish post introduction of Trojan fish infected with IPNV via intraperitoneal injection.
Identification of Moen SNP4 associated with IPNV-resistance using restriction digestion and melt curve analysis. All products create two melt peaks (derivatives 1 and 2) to provide a derivative ratio that predicts homozygote C (high derivative ratio), heterozygote CT (medium derivative ratio), and homozygote T (low ratio).